MARCH8 Antibody - N-terminal region : FITC (ARP75860_P050-FITC)
Selected Variant
ARP75860_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Membrane associated ring-CH-type finger 8
Gene Aliases
MIR, CMIR, c-MIR, MARCH8, RNF178, MARCH-VIII
Gene ID
220972
Swiss Prot
Q5T0T0
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MARH8
Target
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]) .[supplied by OMIM, Apr 2010]
Partner Proteins
TNFRSF10A; UBC; UBE2H; UBE2D1; TFRC; UBE2D3; IL1RAP; IL1R1; CD86
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
Shipping Conditions
Wet Ice
Protein Length
291
NCBI Gene Symbol
44993
NCBI GB Accession Number
MARCH8
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase MARCH8
Peptide Sequence
MSMPLHQISAIPSQDAISARVYRSKTKEKEREEQNEKTLGHFMSHSSNIS
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