RITA1 Antibody - C-terminal: Biotin (ARP75828_P050-Biotin)
Product Specifications
Gene Aliases
RITA, C12orf52
Gene ID
84934
Swiss Prot
Q96K30-2
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human RITA1
Target
RITA1is a tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. It shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. And it may play a role in neurogenesis.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/mL
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
19 kDa
Shipping Conditions
Wet Ice
Protein Length
177
NCBI Gene Symbol
RITA1
Curated Selection
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