PHC3 Antibody - C-terminal region : Biotin (ARP75787_P050-Biotin)
Selected Variant
ARP75787_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
EDR3, HPH3
Gene ID
80012
Swiss Prot
Q8NDX5
Accession Number
XP_005247847
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC3
Target
PHC3 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Partner Proteins
OGT; UBC; EED; RNF2; BMI1; SOX2; ALB; CBX2; PHC3; CBX8; CBX6; SCMH1; CBX4; PCGF2; SCML1; RING1; PHC2; PHC1; SUMO2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
108kDa
Shipping Conditions
Wet Ice
Protein Length
983
NCBI Gene Symbol
PHC3
NCBI GB Accession Number
PHC3
Host or Source
Rabbit
Peptide Sequence
LSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHE
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