RNASEH2B Antibody - C-terminal region : FITC (ARP75764_P050-FITC)
Selected Variant
ARP75764_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Ribonuclease H2 subunit B
Gene Aliases
AGS2, DLEU8
Gene ID
79621
Swiss Prot
Q5TBB1
Accession Number
NP_078846
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human RNH2B
Target
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2) .
Partner Proteins
UBC; ANP32E; UBQLN2; RDX; DNAJB1; RNASEH2C; RNASEH2A; NRAS
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
Shipping Conditions
Wet Ice
Protein Length
312
NCBI Gene Symbol
RNASEH2B
NCBI GB Accession Number
RNASEH2B
Host or Source
Rabbit
Protein Name
Ribonuclease H2 subunit B
Peptide Sequence
SKYLKLPEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSK
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