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PDLIM2 Antibody - C-terminal region : HRP (ARP75738_P050-HRP)

Selected Variant

ARP75738_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

PDZ and LIM domain 2

Gene Aliases

SLIM, MYSTIQUE

Gene ID

64236

Swiss Prot

Q96JY6-4

Accession Number

NP_932159

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDLI2

Target

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

ACD; POT1; UBC; RELA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

Shipping Conditions

Wet Ice

Protein Length

278

NCBI Gene Symbol

PDLIM2

NCBI GB Accession Number

PDLIM2

Host or Source

Rabbit

Protein Name

PDZ and LIM domain protein 2

Peptide Sequence

VLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS

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