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TFIP11 Antibody - N-terminal region : Biotin (ARP75496_P050-Biotin)

Selected Variant

ARP75496_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Tuftelin interacting protein 11

Gene Aliases

NTR1, STIP, TIP39, STIP-1, Spp382, bK445C9.6

Gene ID

24144

Swiss Prot

Q9UBB9

Accession Number

NP_036275

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human TFP11

Target

This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

Shipping Conditions

Wet Ice

Protein Length

837

NCBI Gene Symbol

TFIP11

NCBI GB Accession Number

TFIP11

Host or Source

Rabbit

Protein Name

Tuftelin-interacting protein 11

Peptide Sequence

SHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGV

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