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SMG6 Antibody - middle region : Biotin (ARP75465_P050-Biotin)

Selected Variant

ARP75465_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

SMG6, nonsense mediated mRNA decay factor

Gene Aliases

EST1A, SMG-6, C17orf31, hSMG5/7a

Gene ID

23293

Swiss Prot

Q86US8

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human EST1A

Target

This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.

Partner Proteins

UBC; SOX2; PPP1CC; gag-pol; UPF1; HBB; HDAC8; TERT; SMG5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

156kDa

Shipping Conditions

Wet Ice

Protein Length

1419

NCBI Gene Symbol

SMG6

NCBI GB Accession Number

SMG6

Host or Source

Rabbit

Protein Name

Telomerase-binding protein EST1A

Peptide Sequence

DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQY

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