SMG6 Antibody - middle region : Biotin (ARP75465_P050-Biotin)
Selected Variant
ARP75465_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
SMG6, nonsense mediated mRNA decay factor
Gene Aliases
EST1A, SMG-6, C17orf31, hSMG5/7a
Gene ID
23293
Swiss Prot
Q86US8
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human EST1A
Target
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.
Partner Proteins
UBC; SOX2; PPP1CC; gag-pol; UPF1; HBB; HDAC8; TERT; SMG5
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
156kDa
Shipping Conditions
Wet Ice
Protein Length
1419
NCBI Gene Symbol
SMG6
NCBI GB Accession Number
SMG6
Host or Source
Rabbit
Protein Name
Telomerase-binding protein EST1A
Peptide Sequence
DEVSPTSWGDSRQAQASYYKFQNSDNPYYYPRTPGPASQYPYTGYNPLQY
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