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WAPL Antibody - middle region : HRP (ARP75435_P050-HRP)

Selected Variant

ARP75435_P050-HRP

Size: 100 µL

Product Specifications

Gene Aliases

FOE, WAPAL, KIAA0261

Gene ID

23063

Swiss Prot

Q7Z5K2

Accession Number

NP_055860

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human WAPL

Target

WAPL is a regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. It is involved in both sister chromatid cohesion during interphase and sister- chromatid resolution during early stages of mitosis. It couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

Partner Proteins

UBC; RPA3; RPA2; RPA1; XRN1; PDS5A; SMC3; VCP; VPS16; WRAP53; USP15; USP10; NSMCE2; ELAVL1; SUMO2; RAD21; ARAP1; Stag2; WAPAL; PDS5B; STAG1; SMC1A; SRRM1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

130kDa

Shipping Conditions

Wet Ice

Protein Length

1190

NCBI Gene Symbol

WAPL

NCBI GB Accession Number

WAPL

Host or Source

Rabbit

Peptide Sequence

KSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDD

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