SCAP Antibody - C-terminal region : FITC (ARP75421_P050-FITC)
Selected Variant
ARP75421_P050-FITC
Size: 100 µL
Product Specifications
Gene Aliases
SCAP, KIAA0199, PSEC0227
Gene ID
22937
Swiss Prot
Q12770
Accession Number
XP_006713097
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCAP
Target
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Partner Proteins
ERLIN2; INSIG1; UBC; INSIG2; SREBF2; SREBF1; RNF139; SEC24B; SCAP; PGRMC1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
140kDa
Shipping Conditions
Wet Ice
Protein Length
1279
NCBI Gene Symbol
SCAP
NCBI GB Accession Number
SCAP
Host or Source
Rabbit
Peptide Sequence
GPPPPSLFGDQPDLTCLIDTNFSAQPRSSQPTQPEPRHRAVCGRSRDSPG
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