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MAML1 Antibody - middle region : Biotin (ARP75292_P050-Biotin)

Selected Variant

ARP75292_P050-Biotin

Size: 100 µL

Product Specifications

Gene Aliases

Mam1, Mam-1

Gene ID

9794

Swiss Prot

Q92585

Accession Number

NP_055572

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human MAML1

Target

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Partner Proteins

Su (H) ; NOTCH1; RBPJ; PBRM1; PHF8; SMARCA4; HDAC9; PIAS1; MAML1; CDK8; EP300; NOTCH3; NOTCH2; CREBBP; NOTCH4; MAML2; MAML3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

111kDa

Shipping Conditions

Wet Ice

Protein Length

1016

NCBI Gene Symbol

MAML1

NCBI GB Accession Number

MAML1

Host or Source

Rabbit

Peptide Sequence

VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLS

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