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MAML1 Antibody - middle region: Biotin (ARP75292_P050-Biotin)

Product Specifications

Gene Aliases

Mam1, Mam-1

Gene ID

9794

Swiss Prot

Q92585

Accession Number

NP_055572

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human MAML1

Target

This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Partner Proteins

Su (H) ; NOTCH1; RBPJ; PBRM1; PHF8; SMARCA4; HDAC9; PIAS1; MAML1; CDK8; EP300; NOTCH3; NOTCH2; CREBBP; NOTCH4; MAML2; MAML3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/mL

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

111kDa

Shipping Conditions

Wet Ice

Protein Length

1016

NCBI Gene Symbol

MAML1

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