RAPGEF5 Antibody - middle region : FITC (ARP75290_P050-FITC)
Selected Variant
ARP75290_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Rap guanine nucleotide exchange factor 5
Gene Aliases
GFR, REPAC, MR-GEF
Gene ID
9771
Swiss Prot
Q92565-2
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human RPGF5
Target
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]) .[supplied by OMIM, Mar 2008]
Partner Proteins
TMEM253; PLAC9; VANGL1; KCND3; MRAS; RAP2B; RAP2A; RAP1A
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
Shipping Conditions
Wet Ice
Protein Length
444
NCBI Gene Symbol
RAPGEF5
NCBI GB Accession Number
RAPGEF5
Host or Source
Rabbit
Protein Name
Rap guanine nucleotide exchange factor 5
Peptide Sequence
GMHRRHTVDEYSPQKKNKALFHQFSLKENWLQHRGTVTETEEIFCHVYIT
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