USP14 Antibody - C-terminal region: FITC (ARP75237_P050-FITC)

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UBC; UBP6; PSMD2; HTT; ERN1; CLB1; SHFM1; RPL23; RPL30; RAP1GDS1; GSS; ECHS1; CNDP2; RNF11; PFAS; HNRNPK; VPS37B; UNC45A; WDR12; XPO7; PSMD14; XPO1; UBE3A; UBE2N; PSMD13; PSMD12; PSMD7; PSMC6; PSMC4; PSMC3; USP28; USP21; USP15; PSMD4; PSMA2; RAD23A; PSMC5

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.