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ORC4 Antibody - C-terminal region : FITC (ARP75011_P050-FITC)

Selected Variant

ARP75011_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

ORC4L, ORC4P

Gene ID

5000

Swiss Prot

O43929

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ORC4

Target

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.

Partner Proteins

RRM2B; TCF4; MCM3; MTUS1; MCM10; FBXL8; FBXO6; FBXO25; FBXL5; ORC3; ORC6; UBC; ORC5; ORC2; MLH1; MCM7; KPNA1; CTBP1; CDKN2A; CCND1; APP; XRCC5; XRCC6; CCL2; tat; MCM2; ORC1; MCM6; MCM4; DBF4; RPA2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Protein Length

436

NCBI Gene Symbol

ORC4

NCBI GB Accession Number

ORC4

Host or Source

Rabbit

Peptide Sequence

IIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEH

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