ORC4 Antibody - C-terminal region : FITC (ARP75011_P050-FITC)
Selected Variant
ARP75011_P050-FITC
Size: 100 µL
Product Specifications
Gene Aliases
ORC4L, ORC4P
Gene ID
5000
Swiss Prot
O43929
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ORC4
Target
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
Partner Proteins
RRM2B; TCF4; MCM3; MTUS1; MCM10; FBXL8; FBXO6; FBXO25; FBXL5; ORC3; ORC6; UBC; ORC5; ORC2; MLH1; MCM7; KPNA1; CTBP1; CDKN2A; CCND1; APP; XRCC5; XRCC6; CCL2; tat; MCM2; ORC1; MCM6; MCM4; DBF4; RPA2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
Shipping Conditions
Wet Ice
Protein Length
436
NCBI Gene Symbol
ORC4
NCBI GB Accession Number
ORC4
Host or Source
Rabbit
Peptide Sequence
IIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEH
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