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HLCS Antibody - C-terminal region : HRP (ARP74943_P050-HRP)

Selected Variant

ARP74943_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Holocarboxylase synthetase (biotin- (proprionyl-CoA-carboxylase (ATP-hydrolysing) ) ligase)

Gene Aliases

HCS

Gene ID

3141

Swiss Prot

P50747

Accession Number

XP_006724059.1

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen for Anti-HLCS antibody is: synthetic peptide directed towards the C-terminal region of Human BPL1

Target

This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

79 kDa

Shipping Conditions

Wet Ice

Protein Length

726

NCBI Gene Symbol

HLCS

NCBI GB Accession Number

HLCS

Host or Source

Rabbit

Peptide Sequence

MSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLVNSTLMGETF

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