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GRB10 Antibody - N-terminal region : FITC (ARP74938_P050-FITC)

Selected Variant

ARP74938_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

RSS, IRBP, MEG1, GRB-IR, Grb-10

Gene ID

2887

Swiss Prot

Q13322

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human GRB10

Target

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

65 kDa

Shipping Conditions

Wet Ice

Protein Length

594

NCBI Gene Symbol

GRB10

NCBI GB Accession Number

GRB10

Host or Source

Rabbit

Peptide Sequence

DDVDLEALVNDMNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPR

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