MAP4 Antibody - N-terminal region: Biotin (ARP74631_P050-Biotin)

The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU) . This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene.

UBC; LGR4; RPA3; RPA2; RPA1; LSM8; WDHD1; HNRNPR; PDCD6; PPP4R1; MTA2; POLR2C; POLR2A; IARS; HNRNPF; EIF2S1; CSTF2; COG7; TARDBP; BAG3; ERBB2IP; SNTA1; LDLR; IL7R; FN1; TRAF3IP1; RPS20; GRK5; EPS15; AP2M1; USP21; CUL4A; POT1; ISG15; TERF1; SIRT7; SH3KBP1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.