EIF4EBP1 Antibody - C-terminal region : FITC (ARP74511_P050-FITC)

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Mtor; MLST8; RPTOR; TCF4; REL; EIF4E; RICTOR; MAPKAP1; UBC; SLMAP; LATS1; PRKDC; ATM; PPP2R4; STK3; MAPK14; LRRK2; AGO2; MAPK1; KLHL25; IRAK4; PRKCA; GSK3B; CHTF8; RHEBL1; RPS6KB1; MAPKAPK5; PPP2CA; RPS6KA5; EIF4E2; MVD; RORC; BUB1; AKT1; CSNK2A2; CSNK2A1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.