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SIRT3 Antibody - N-terminal region : FITC (ARP74220_P050-FITC)

Selected Variant

ARP74220_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Sirtuin 3

Gene Aliases

SIR2L3

Gene ID

23410

Swiss Prot

Q9NTG7

Accession Number

NP_036371

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human SIR3

Target

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Partner Proteins

SIRT5; SKP2; UBC; HSPD1; CMYA5; PGAP1; RIF1; NCAPD2; HERC2; TTF2; UQCRH; UGDH; HSP90B1; SNTB1; SBF1; HSPA9; HSPA5; HSPA4; HSPA1L; GRN; ATP5B; ATP5A1; SIRT4; tat; XRCC6; FOXO3; DNM1L; PEX5

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Protein Length

399

NCBI Gene Symbol

SIRT3

NCBI GB Accession Number

SIRT3

Host or Source

Rabbit

Protein Name

NAD-dependent protein deacetylase sirtuin-3, mitochondrial

Peptide Sequence

AAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRA

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