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SEC61B Antibody - N-terminal region : FITC (ARP74207_P050-FITC)

Selected Variant

ARP74207_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Sec61 translocon beta subunit

Gene ID

10952

Swiss Prot

P60468

Accession Number

NP_006799

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human SC61B

Target

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

Partner Proteins

LOC100355886; ASNA1; BAG6; HSPA8; DNAJB1; HSPA4; ERLIN2; SGTA; EGFR; UBC; OST4; AMFR; ITGA4; FN1; ESR1; SEC61B; EDEM1; AGER; ATP13A2; SPC25; SEC61A1; BCAP31; GET4; UBL4A; SERP1; ARL6; SEC63; TRAM1; APOB; VCAM1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

10kDa

Shipping Conditions

Wet Ice

Protein Length

96

NCBI Gene Symbol

SEC61B

NCBI GB Accession Number

SEC61B

Host or Source

Rabbit

Protein Name

Protein transport protein Sec61 subunit beta

Peptide Sequence

PTPSGTNVGSSGRSPSKAVAARAAGSTVRQRKNASCGTRSAGRTTSAGTG

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