SEC61B Antibody - N-terminal region: Biotin (ARP74207_P050-Biotin)

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript.

LOC100355886; ASNA1; BAG6; HSPA8; DNAJB1; HSPA4; ERLIN2; SGTA; EGFR; UBC; OST4; AMFR; ITGA4; FN1; ESR1; SEC61B; EDEM1; AGER; ATP13A2; SPC25; SEC61A1; BCAP31; GET4; UBL4A; SERP1; ARL6; SEC63; TRAM1; APOB; VCAM1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.