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DEDD Antibody - middle region: FITC (ARP73942_P050-FITC)

Product Specifications

Gene Aliases

DEFT, KE05, DEDD1, FLDED1, CASP8IP1

Gene ID

9191

Swiss Prot

O75618

Accession Number

NP_127491

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human DEDD

Target

This gene encodes a protein that contains a death effector domain (DED) . DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Partner Proteins

APLP2; SMAD3; BATF2; SHMT1; APP; UBC; HOXD4; USP22; DEDD2; GTF3C1; CFLAR; FADD; CASP8; CASP10; CASP3; KRT18; KRT8; GTF3C3; DEDD; CCDC59; RANBP3; KHK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

Shipping Conditions

Wet Ice

Protein Length

318

NCBI Gene Symbol

DEDD

Curated Selection

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