DEDD Antibody - middle region: FITC (ARP73942_P050-FITC)
Product Specifications
Gene Aliases
DEFT, KE05, DEDD1, FLDED1, CASP8IP1
Gene ID
9191
Swiss Prot
O75618
Accession Number
NP_127491
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human DEDD
Target
This gene encodes a protein that contains a death effector domain (DED) . DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Partner Proteins
APLP2; SMAD3; BATF2; SHMT1; APP; UBC; HOXD4; USP22; DEDD2; GTF3C1; CFLAR; FADD; CASP8; CASP10; CASP3; KRT18; KRT8; GTF3C3; DEDD; CCDC59; RANBP3; KHK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
Shipping Conditions
Wet Ice
Protein Length
318
NCBI Gene Symbol
DEDD
Curated Selection
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