CDC25B Antibody - C-terminal region : HRP (ARP73924_P050-HRP)

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.

BTRC; UBC; FBXW11; MAPK9; CDK5; CDK1; YWHAQ; MAPKAPK2; UBD; BRSK2; CDC14A; CDK2; Cdc25b; FOXM1; BRSK1; FHL3; KAT2B; MELK; YWHAE; CHEK1; AURKA; SFN; YWHAB; YWHAZ; MAPK14; CREBBP; AR; ESR1; CSNK2B; CSNK2A1; YWHAH; PGR; PHB2; KRT85; KRT35; KRT31

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.