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SF3A2 Antibody - N-terminal region : HRP (ARP73890_P050-HRP)

Selected Variant

ARP73890_P050-HRP

Size: 100 µL

Product Specifications

Gene Aliases

PRP11, SAP62, PRPF11, SF3a66

Gene ID

8175

Swiss Prot

Q15428

Accession Number

NP_009096

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human SF3A2

Target

This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Partner Proteins

UBC; WWOX; rev; PRPF40A; WBP4; TCERG1; APBB1; HECW2; PAN2; SMURF2; SF3A1; PRPF31; NIPBL; SF3B1; SF3B3; SF3B2; SF3A3; PRPF8; PPIE; PRPF3; SART1; TPM3; SNRPA1; SUMO1; SUMO3; CUL3; ISG15; RBM17; PHF5A; NRIP2; SF3B5; C19orf43; PQBP1; DDX46; RBM39; DDX23; EFTU

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

Shipping Conditions

Wet Ice

Protein Length

464

NCBI Gene Symbol

SF3A2

NCBI GB Accession Number

SF3A2

Host or Source

Rabbit

Peptide Sequence

GGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECK

Price

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