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REV1 Antibody - C-terminal region : FITC (ARP73719_P050-FITC)

Selected Variant

ARP73719_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

REV1L, AIBP80

Gene ID

51455

Swiss Prot

Q9UBZ9

Accession Number

XP_005264024

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human REV1

Target

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.

Partner Proteins

RELA; POLD3; MSH2; REV3L; BRCA1; PCNA; MAD2L2; POLH; UBC; CDC27; REV1; POLK; POLI; C1orf86; MYC; HSP90AB1; HSP90AA1; POLDIP2; POLL; FHL2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

137kDa

Shipping Conditions

Wet Ice

Protein Length

1251

NCBI Gene Symbol

REV1

NCBI GB Accession Number

REV1

Host or Source

Rabbit

Peptide Sequence

INLIALPAFSQVDPEVFAALPAELQRELKAAYDQRQRQGENSTHQQSASA

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