IFI16 Antibody - middle region: HRP (ARP72649_P050-HRP)
Product Specifications
Gene Aliases
PYHIN2, IFNGIP1
Gene ID
3428
Swiss Prot
Q16666-2
Accession Number
NP_005522
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human IFI16
Target
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; MDM2; IGSF8; ICAM1; WHSC1; NOTCH1; APP; BRCA1; SP1; SUMO2; ID1; TPR; TP53BP1; ID2; ID3; AR; TP53; CSNK2A1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
82kDa
Shipping Conditions
Wet Ice
Protein Length
729
NCBI Gene Symbol
IFI16
Curated Selection
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