SP100 Antibody - middle region: FITC (ARP72581_P050-FITC)
Product Specifications
Gene Aliases
Lysp100b
Gene ID
6672
Swiss Prot
P23497
Accession Number
NP_003104
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human SP100
Target
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) -SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
Partner Proteins
RBM39; DYRK2; SUMO1; UBE2I; SP100; SUMO2; SUMO3; PHC1; DNMT3A; ACTN2; RTP5; L3MBTL3; TRAF3IP3; GIPC2; AMOTL2; ZC2HC1A; SENP1; CBX5; USPL1; UBC; PML; VPS25; PUS1; CRTAP; TOM1L1; SERPINE2; AGL; CREM; DSTN; AHCYL1; SEC23A; IGBP1; ETS1; ARID3A; TERF2IP; TERF2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
96kDa
Shipping Conditions
Wet Ice
Protein Length
879
NCBI Gene Symbol
SP100
Curated Selection
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