XRCC1 Antibody - C-terminal region : Biotin (ARP72538_P050-Biotin)

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

UBC; RPA3; RPA2; RPA1; EED; PNKP; APTX; POLB; CSNK2A1; S100A16; SEPT11; UBAP2L; SEC22B; TIMELESS; MRPL12; RBM4; PPT1; CAND1; SUMO1; Cebpb; POLI; XPO1; SUMO2; PARP1; RNF146; ARL6IP5; POLK; POLD1; PCNA; LIG3; RAN; NCAPG; CHD1L; NEIL1; APLF; PARP2; OGG1; CSN

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.