CASP9 Antibody - middle region : FITC (ARP72517_P050-FITC)

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

BAX; XIAP; BIRC2; APAF1; BIRC8; BIRC7; ABL1; PTCH1; CRYAB; SQSTM1; JUN; CASP7; CASP3; BRCA1; RB1; MSTO1; HSD17B4; BIRC3; VCP; BIRC6; UBC; RNF2; MZB1; CARD8; GMEB1; NAIP; NLRP1; NOD1; DIABLO; BCL10; BIRC5; ILK; CASP9; MAPK3; HIP1; CASP10; MAP2K2; SRF; BCL2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.