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PSMD5 Antibody - C-terminal region: FITC (ARP71476_P050-FITC)

Product Specifications

Gene Aliases

S5B

Gene ID

5711

Swiss Prot

Q16401

Accession Number

NP_005038

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PSMD5

Target

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

Partner Proteins

UBC; TFCP2; PSMC2; PSMC1; PPME1; GMPS; PNP; PARK2; RNF11; BAG3; FN1; MACF1; PSMD13; PSMD7; PSMD2; PSMD1; PSMB5; PSMB4; PSMB2; PSMB1; PSMA7; PSMA6; PSMA4; PSMA2; PSMA1; APP; PSMD4; COPS2; RAD23A; ELAVL1; PMS2; RPN7; RPN2; RPT1; RPT2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PSMD5 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

55kDa

Shipping Conditions

Wet Ice

Protein Length

504

NCBI Gene Symbol

PSMD5

Nucleotide Accession Number

NM_005047

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