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MRPL30 Antibody - C-terminal region : FITC (ARP70883_P050-FITC)

Selected Variant

ARP70883_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

L28MT, L30MT, MRPL28, RPML28, MRP-L28, MRP-L30, MRPL28M

Gene ID

51263

Swiss Prot

Q8TCC3

Accession Number

NP_660213

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPL30

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene.

Partner Proteins

MARCKSL1; PLP2; SLC25A3; UBC

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 80%; Human: 100%; Mouse: 91%; Rabbit: 89%; Rat: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

Shipping Conditions

Wet Ice

Protein Length

161

NCBI Gene Symbol

MRPL30

NCBI GB Accession Number

MRPL30

Host or Source

Rabbit

Protein Name

39S ribosomal protein L30, mitochondrial

Nucleotide Accession Number

NM_145212

Peptide Sequence

VVKHLIRIKPLKLPQGLPAEENMSNTCLKSTGELVVQWHLKPVEQKAHES

Price

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