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PTK2 Antibody - middle region : FITC (ARP70875_P050-FITC)

Selected Variant

ARP70875_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

FAK, FADK, FAK1, FRNK, FADK 1, PPP1R71, p125FAK, pp125FAK

Gene ID

5747

Swiss Prot

Q05397-4

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human PTK2

Target

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Partner Proteins

DEF6; SOCS3; YES1; IQGAP1; UBE2H; UBC; TRIM72; SRPK1; PXN; PTRH2; SAE1; HSP90AA1; APP; RBSN; BCAR1; KCNJ3; PTAFR; STAT1; CBL; STAP2; STUB1; PTPN11; PPP1CB; PPP1CA; SRC; CTTN; ASAP1; SH3KBP1; PDCD6IP; ITGB5; ELAVL1; DAG1; GRB2; FBP1; F13A1; EEF1G; LPXN; TG

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

47kDa

Shipping Conditions

Wet Ice

Protein Length

431

NCBI Gene Symbol

PTK2

NCBI GB Accession Number

PTK2

Host or Source

Rabbit

Protein Name

Focal adhesion kinase 1

Peptide Sequence

SEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRER IELGRC

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