PTK2 Antibody - middle region : FITC (ARP70875_P050-FITC)
Selected Variant
ARP70875_P050-FITC
Size: 100 µL
Product Specifications
Gene Aliases
FAK, FADK, FAK1, FRNK, FADK 1, PPP1R71, p125FAK, pp125FAK
Gene ID
5747
Swiss Prot
Q05397-4
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PTK2
Target
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Partner Proteins
DEF6; SOCS3; YES1; IQGAP1; UBE2H; UBC; TRIM72; SRPK1; PXN; PTRH2; SAE1; HSP90AA1; APP; RBSN; BCAR1; KCNJ3; PTAFR; STAT1; CBL; STAP2; STUB1; PTPN11; PPP1CB; PPP1CA; SRC; CTTN; ASAP1; SH3KBP1; PDCD6IP; ITGB5; ELAVL1; DAG1; GRB2; FBP1; F13A1; EEF1G; LPXN; TG
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
Shipping Conditions
Wet Ice
Protein Length
431
NCBI Gene Symbol
PTK2
NCBI GB Accession Number
PTK2
Host or Source
Rabbit
Protein Name
Focal adhesion kinase 1
Peptide Sequence
SEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRER IELGRC
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