FBXL15 Antibody - N-terminal region : Biotin (ARP70412_P050-Biotin)
Product Specifications
Gene Aliases
JET, PSD, Fbl15, FBXO37
Gene ID
79176
Swiss Prot
Q9H469
Accession Number
NP_077302
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
Target
FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Partner Proteins
HNRNPD; SKP1; ITCH; SMURF2; HECW2; SMURF1; NEDD4L; HECW1; WWP2; WWP1; RBX1; CUL1; NEDD4; HSP90AA1; COPS6; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-FBXL15 (ARP70412_P050-Biotin) antibody
Protein Length
300
NCBI Gene Symbol
FBXL15
NCBI GB Accession Number
FBXL15
Host or Source
Rabbit
Protein Name
F-box/LRR-repeat protein 15
Nucleotide Accession Number
NM_024326
Peptide Sequence
PPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFR
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