FBXL15 Antibody - N-terminal region : Biotin (ARP70412_P050-Biotin)
Selected Variant
ARP70412_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
JET, PSD, Fbl15, FBXO37
Gene ID
79176
Swiss Prot
Q9H469
Accession Number
NP_077302
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
Target
FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.
Partner Proteins
HNRNPD; SKP1; ITCH; SMURF2; HECW2; SMURF1; NEDD4L; HECW1; WWP2; WWP1; RBX1; CUL1; NEDD4; HSP90AA1; COPS6; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
Shipping Conditions
Wet Ice
Protein Length
300
NCBI Gene Symbol
FBXL15
NCBI GB Accession Number
FBXL15
Host or Source
Rabbit
Protein Name
F-box/LRR-repeat protein 15
Nucleotide Accession Number
NM_024326
Peptide Sequence
PPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFR
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