Biotinylated Mouse IL-11 R alpha Protein, Avitag™
Receptor for interleukin-11 (IL11) . The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable) . Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
Product Specifications
Background
Specifications
Accession Number
Q64385-1
Expression Region
Cys 26 - Gln 367
Host
HEK293
Target
IL-11 R alpha
Conjugation
Biotin-labeled
Tag
C-Avi
Source
Mouse
Stability
Endotoxin
1.0 EU per μg
Purity
85%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
39.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*2
Host or Source
HEK293
Species
Mouse
Protein ID
Q64385-1
Preservative
Trehalose
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