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NDUFA12 Antibody - N-terminal region: Biotin (ARP68751_P050-Biotin)

Product Specifications

Gene Aliases

B17.2, DAP13, MC1DN23

Gene ID

55967

Swiss Prot

Q9UI09

Accession Number

NP_061326

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human NDUFA12

Target

This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC; MMGT1; TOMM22; MRPL15; ERLIN1; ATP5H; SURF1; NDUFS4; NDUFS1; NDUFB9; NDUFA9; NDUFA2; MPV17; CYC1; COX15; ATP5C1; ATP5B; ABCD1; ZNF768

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 100%; Yeast: 91%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

145

NCBI Gene Symbol

NDUFA12

Protein Name

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Nucleotide Accession Number

NM_018838

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