PARPBP Antibody - C-terminal region: Biotin (ARP68105_P050-Biotin)
Product Specifications
Gene Name
PARP1 binding protein
Gene Aliases
AROM, PARI, C12orf48
Gene ID
55010
Swiss Prot
Q9NWS1-5
Host
Rabbit
Reactivity
Human, Rat, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP
Target
PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. PARPBP antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly (A) homopolymers and positively regulate the poly (ADP-ribosyl) ation activity of PARP1; however such function may be indirect.
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Horse: 85%; Human: 100%; Pig: 92%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
Shipping Conditions
Wet Ice
Protein Length
294
NCBI Gene Symbol
PARPBP
Protein Name
PCNA-interacting partner
Curated Selection
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