TTI2 Antibody - N-terminal region : Biotin (ARP68059_P050-Biotin)
Selected Variant
ARP68059_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
MRT39, C8orf41
Gene ID
80185
Swiss Prot
Q6NXR4
Accession Number
NP_079391
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TTI2
Target
TTI2 is a regulator of the DNA damage response (DDR) . 'TTI2 is part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . 'TTI2, together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Partner Proteins
FUS; UBC; SUMO1; NEDD8; EGFR; ELAVL1; RPAP3; PIH1D1; RUVBL2; TELO2; TTI1; RUVBL1; PRKDC; HSP90AA1; HSPA4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 92%; Guinea Pig: 75%; Horse: 100%; Human: 100%; Pig: 92%; Rabbit: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
Shipping Conditions
Wet Ice
Protein Length
508
NCBI Gene Symbol
TTI2
NCBI GB Accession Number
TTI2
Host or Source
Rabbit
Protein Name
TELO2-interacting protein 2
Nucleotide Accession Number
NM_025115
Peptide Sequence
THSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSV
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