YTHDF2 Antibody - C-terminal region: FITC (ARP67917_P050-FITC)
Product Specifications
Gene Aliases
DF2, CAHL, HGRG8, NY-REN-2
Gene ID
51441
Swiss Prot
Q9Y5A9
Accession Number
NP_057342
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human YTHDF2
Target
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.
Partner Proteins
UBC; RPA3; RPA2; RPA1; RNF2; BMI1; EIF3H; EIF3A; FBXO6; TARDBP; HIPK4; VCAM1; FN1; EPAS1; ESR1; APP; SMAD3; CAND1; CUL3; ELAVL1; POT1; MEPCE; HNRNPH1; HNRNPA1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
YTHDF2 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
Shipping Conditions
Wet Ice
Protein Length
579
NCBI Gene Symbol
YTHDF2
Protein Name
YTH domain family protein 2
Nucleotide Accession Number
NM_016258
Curated Selection
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