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MRPS7 Antibody - C-terminal region : Biotin (ARP67679_P050-Biotin)

Selected Variant

ARP67679_P050-Biotin

Size: 100 µL

Product Specifications

Gene Aliases

S7mt, MRP-S, RP-S7, RPMS7, MRP-S7, COXPD34, bMRP27a

Gene ID

51081

Swiss Prot

Q9Y2R9

Accession Number

NP_057055

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MRPS7

Target

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p.

Partner Proteins

CEP76; TUBGCP4; TUBGCP3; CEP57; TUBG1; GRSF1; UBC; SMURF2; RNF2; PARK2; C1QBP; MRPL54; MRPL1; MRPS9; MRPS25; RNMTL1; MRPL28; TUFM; PSMA5; HNRNPAB; EEF1A1; ACTA2; CAND1; CUL3; Cdca8; Ybx1; ICT1; ASF1B

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MRPS7 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Protein Length

242

NCBI Gene Symbol

MRPS7

NCBI GB Accession Number

MRPS7

Host or Source

Rabbit

Protein Name

28S ribosomal protein S7, mitochondrial

Nucleotide Accession Number

NM_015971

Peptide Sequence

QFEKYHAASAEEQATIERNPYTIFHQALKNCEPMIGLVPILKGGRFYQVP

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