IQSEC2 Antibody - middle region: Biotin (ARP67590_P050-Biotin)
Product Specifications
Gene Aliases
MRX1, BRAG1, MRX18, MRX78, IQ-ArfGEF
Gene ID
23096
Swiss Prot
Q5JU85-2
Accession Number
NP_001104595
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human IQSEC2
Target
This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation.
Partner Proteins
UBC; ELAVL1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
IQSEC2 is supported by BioGPS gene expression data to be expressed in MDA-MB435
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
163kDa
Shipping Conditions
Wet Ice
Protein Length
1488
NCBI Gene Symbol
IQSEC2
Protein Name
IQ motif and SEC7 domain-containing protein 2
Nucleotide Accession Number
NM_001111125
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