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CCDC99 Antibody - C-terminal region : Biotin (ARP67438_P050-Biotin)

Product Specifications

Gene Aliases

CCDC99

Gene ID

54908

Swiss Prot

Q96EA4

Accession Number

NP_060255

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCDC99

Target

CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. CCDC99 is also required for correct spindle orientation. It does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

Partner Proteins

RTP5; PPP1R18; DYX1C1; SPDL1; USP15; TRAF4; CA8; NEK9; SIRT1; HMGCS1; DHX40; YLPM1; SF3B3; ITSN1; UBC; KIAA1377; GPS2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SPDL1 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 93%; Horse: 92%; Human: 100%; Pig: 93%; Rabbit: 86%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-SPDL1 (ARP67438_P050-Biotin) antibody

Protein Length

605

NCBI Gene Symbol

SPDL1

NCBI GB Accession Number

SPDL1

Host or Source

Rabbit

Protein Name

Protein Spindly

Nucleotide Accession Number

NM_017785

Peptide Sequence

PRLAAESKLQTEVKEGKETSSKLEKETCKKLHPILYVSSKSTPETQCPQQ

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