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ATXN7L3 Antibody - middle region : HRP (ARP67018_P050-HRP)

Selected Variant

ARP67018_P050-HRP

Size: 100 µL

Product Specifications

Gene Aliases

SGF11

Gene ID

56970

Swiss Prot

Q14CW9

Accession Number

NP_064603

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human ATXN7L3

Target

ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

Partner Proteins

SIRT1; USP22; SECISBP2; SERTAD1; PICK1; USP6; UCHL3; HIST2H2BE; HIST2H2AC; ATXN7; KAT2A; ENY2; TAF5L; SUPT3H; TRRAP; TAF10

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

Shipping Conditions

Wet Ice

Protein Length

354

NCBI Gene Symbol

ATXN7L3

NCBI GB Accession Number

ATXN7L3

Host or Source

Rabbit

Protein Name

Ataxin-7-like protein 3

Nucleotide Accession Number

NM_020218

Peptide Sequence

MNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKLWYLPFQNPNSPRRSK

Price

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