IYD Antibody - N-terminal region : FITC (ARP66837_P050-FITC)
Selected Variant
ARP66837_P050-FITC
Size: 100 µL
Product Specifications
Gene Aliases
TDH4, IYD-1, DEHAL1, C6orf71
Gene ID
389434
Swiss Prot
Q6PHW0-3
Accession Number
NP_001158167
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human IYD
Target
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.
Partner Proteins
TRIM69
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 77%; Dog: 79%; Human: 100%; Rabbit: 79%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
247
NCBI Gene Symbol
IYD
NCBI GB Accession Number
IYD
Host or Source
Rabbit
Protein Name
Iodotyrosine dehalogenase 1
Nucleotide Accession Number
NM_001164695
Peptide Sequence
NADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENV
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