TOP1MT Antibody - C-terminal region : FITC (ARP66489_P050-FITC)
Product Specifications
Gene ID
116447
Swiss Prot
Q969P6
Accession Number
NP_443195
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human TOP1MT
Target
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Partner Proteins
SUMO1; FSHR; UBC
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 85%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 85%; Rat: 100%; Yeast: 79%; Zebrafish: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
70kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-TOP1MT (ARP66489_P050-FITC) antibody
Protein Length
601
NCBI Gene Symbol
TOP1MT
NCBI GB Accession Number
TOP1MT
Host or Source
Rabbit
Protein Name
DNA topoisomerase I, mitochondrial
Nucleotide Accession Number
NM_052963
Peptide Sequence
KKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLDPRISIAWCKR
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