NEFM Antibody - C-terminal region : Biotin (ARP66411_P050-Biotin)
Selected Variant
ARP66411_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
NFM, NEF3, NF-M
Gene ID
4741
Swiss Prot
E9PBF7
Accession Number
NP_001099011
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human NEFM
Target
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Partner Proteins
SART3; PARK2; RB1; SMAD2; FOS; IQCB1; SIRT7; UBC; DISC1; TNIK; SQSTM1; MINK1; STXBP1; NEFH; APOE
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 86%; Horse: 86%; Human: 100%; Rabbit: 93%; Rat: 86%; Sheep: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
Shipping Conditions
Wet Ice
Protein Length
540
NCBI Gene Symbol
NEFM
NCBI GB Accession Number
NEFM
Host or Source
Rabbit
Protein Name
Neurofilament medium polypeptide Ensembl ENSP00000412295
Nucleotide Accession Number
NM_001105541
Peptide Sequence
EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVV
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