EIF2B3 Antibody - middle region: Biotin (ARP66344_P050-Biotin)
Product Specifications
Gene Aliases
EIF-2B, EIF2Bgamma
Gene ID
8891
Swiss Prot
Q9NR50
Accession Number
NP_065098
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human EIF2B3
Target
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; C14orf166; RTCB; DIMT1; NELFB; EDC4; IGF2BP3; G3BP1; EIF2B2; EIF3C; YBX3; RFC4; QARS; NMT1; HNRNPM; MRE11A; ILF2; HNRNPU; FLII; FKBP3; DHX9; DDX1; ABCF1; FBXO6; EGFR; EIF2B5; EIF2B4; NDUFB8; EIF2B3; GOLM1; EIF2S2; EIF2S1; STC2; EIF2B1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%; Yeast: 90%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
Shipping Conditions
Wet Ice
Protein Length
452
NCBI Gene Symbol
EIF2B3
Protein Name
Translation initiation factor eIF-2B subunit gamma
Nucleotide Accession Number
NM_020365
Curated Selection
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