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RPLP2 Antibody - N-terminal region : Biotin (ARP66087_P050-Biotin)

Selected Variant

ARP66087_P050-Biotin

Size: 100 µL

Product Specifications

Gene Aliases

P2, LP2, RPP2, D11S2243E

Gene ID

6181

Swiss Prot

P05387

Accession Number

NP_000995

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human RPLP2

Target

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Partner Proteins

TP53; AURKA; TUBGCP4; CEP250; TUBGCP2; CEP57; UBC; TUBG1; MDM2; CNDP2; NANS; NPEPPS; RPL23; FBXO6; YWHAQ; IGSF8; ICAM1; CD81; PAN2; MAPK8; FN1; UBL4A; PA2G4; CTNNB1; HNRNPA3; RPLP0P6; RPS27L; RPL14; UBA52; RPS28; RPS26; RPS25; RPS24; RPS23; RPS21; RPS20

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RPLP2 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 92%; Goat: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

12kDa

Shipping Conditions

Wet Ice

Protein Length

115

NCBI Gene Symbol

RPLP2

NCBI GB Accession Number

RPLP2

Host or Source

Rabbit

Protein Name

60S acidic ribosomal protein P2

Nucleotide Accession Number

NM_001004

Peptide Sequence

MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKN

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