MRPL12 Antibody - middle region : HRP (ARP65790_P050-HRP)

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.

MDM2; PARK2; TARDBP; MRPS27; ICT1; mug82; ADRB2; NPM1; SOX2; OLIG1; POLR1D; UBC; RARG; COX6A2; C1QBP; RPL18; RPL12; RPL11; RPL7A; RBM3; ILF3; HNRNPD; AK2; ACOX1; TMEM9; MRPL10; MRPL52; GADD45GIP1; EPPK1; MRPL1; MRPL9; MRPL11; MRPL41; MRPS9; MRPS26; NIT2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.