DYNC1LI1 Antibody - C-terminal region: Biotin (ARP65751_P050-Biotin)

DYNC1LI1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNC1LI1 may play a role in binding dynein to membranous organelles or chromosomes. DYNC1LI1 is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

REL; BICD2; DYNC1I1; DCTN1; UBC; DYNLRB1; SERBP1; HNRNPA0; AKAP12; DYNLT3; RPS12; PSMD8; PSMC6; EIF3E; FLNA; DYNC1LI2; DYNC1I2; DYNC1H1; vpr; VCP; ZFR; TXNRD1; TKT; DYNLT1; RANGAP1; IKBKG; CUL3; Dynll1; tat; RAB4A; NUP85; PCNT

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.